Prof. František Kopřiva, MD, PhD (CZ)

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Address Fischerova 36 77901 Olomouc, Czech Republic
Telephone 0042585854448

Working Experience :

University teacher since 1993, Occupation or function – Professor
Main working occupation and responsibilities:
Head of children pneumology, laboratories of functional examination and allergology-immunology, children bronchoscopy, research on gene polymorphisms and chronic children diseases, lectures, head of PhD student seminars, Lem laboratories and DK, supervision of postgraduate students
Name and address of employer:
Children Clinic, Puškinova 6, Faculty of Medicine, Palacky University, Olomouc.
Occupational field:
Pediatrics, imunology, pneumology

1999 – until now
Main working occupation and responsibilities:
Professor, work at sick-bed in terms of children clinic, daily round, examination and therapy, scientific office of allegro-immunology and pneumology, functional lung examination, bronchoscopy, diff. Dg of chronic diseases of respiratory system and studies of risk markers and gene polymorfisms in immunopathological disposition in children
Name and address of employer:
Children Clinic, Puškinova 6, Faculty of Medicine, Palacky University, Olomouc

Education, scientific preparation and courses:

1984 – until now Reached qualification – Pediatric professor
1975 – 1981 Faculty of Medicine UP Olomouc, major in general medicine
1984 1st attestation in pediatrics
1988 2nd attestation in pediatrics
1991 Attestation in clinic immunology
1999 Attestation in tuberculosis and respiratory diseases
1999 Defended dissertation thesis, MF UP, major in pediatrics
2003 Habilitation, MLF UP, major in pediatrics
2009 Appointed professor

Name and type of organization which provided education, scientific preparation or course: Faculty of Medicine, Palacky University, Olomouc, ILF Praha
Level of education in national or international classification: Professor, children pneumologist, allergologist immunologist, full graduate pediatrician, PhD

Monographs, Reviewed monographs:
F. Kopřiva Chronický eozinofilní zánět a asthma bonchiale Maxdorf / Jesenius 2003
F. Kopřiva Leukotrieny Úloha v klinické medicině Mechanismy účinku Maxdorf / Jesenius 2005
F. Kopřiva Neurogenní zánět Maxdorf / Jesenius 2009

Award of Dr. Liška – foundation of Dr. Paul Janssen 2004 – for the best scientific work in allergology and clinic immunology in 2003
Award of Prof. Zavázal of the Czech Association of Allergology and Clinic Immunology – 2004 for monograph
Awards of the Dean of Faculty of Medicine for monograph – 2004

1994 – international immunology course Prague
1999 – course of functional lung examination
1999 – course of children flexible bronchoscopy – Davos – prof. Wood
2002 – Postgraduate course of Children Asthma – London
2007 – Visiting professor, Dep. of Experimental Medicíne and Human Genetics, Faculty of Medicine, McGill University

Competencies, knowledge and skills:
Head of laboratory of functional examination of spirometric functions of DK, Bronchoscopy, Scientific secretary of Children Pneymology Association
Lecturer of ČIPA – Czech Initiative for Asthma Bronchiale,Su­pervisor of 2 postgraduate students at the moment
Given about 210 lectures in the Czech Republic and abroad
Published 112 works

Abstracts in magazines and proceedings:
Dissertation thesis: Heterogenity of eosinophils as a marker of eosinophilic inflammation activity
Habilitation thesis: “Eosinophil – inflammation – asthma bronchiale. Current possibilities of laboratory methods of watching the activity of eosinophilic inflammation in children with asthma bronchiale “

1. Heřman M., Michálková K., Kopřiva F.: High-resolution CT in the assesment of bronchiectasis in children,
Pediatr Radiol, 23, 1993, 376 – 379
2. Šantavá A., Zapletalová J., Michálková K., Hanáková St., Kopřiva F., Šantavý J., Dušek J., Kleinová D.:Spondyloepip­hyseal Dysplasia with Nephrotic Syndrome (Schimke Imunoosseus Dysplasia)
American Journal of Medical Genetics, 49, 270 – 273, 1994
3. Kopřiva F. Recurrent herpetic whitlow in a immune competent girl without vesicular lesions.
Eur J Pediatr, 2002, 161, 120 – 121
4. Pohunek P., Matulka M., Rybníček O., Kopřiva F., Honomichlová H., Svobodová T. Dose-related efficacy and safety of formoterol (Oxis) Turbuhaler compared with salmeterol Diskhaler in children with asthma. Paediatric Allergy Immunology, 2004, 15 (1), 32 – 39
5. Kopřiva F, Sobolová L, Szotkowská J, Zápalka M. Treatment of chronic cough in children with montelukast, a leukotriene receptor antagonist.
J Asthma, 2004, 41, 7, 715 – 720
6. Kopřiva, F., Janošťáková A., Szotkowská J., Zápalka M., Hajdůch M.. Montelukast decreases plasma endothelin-1 and serum eosinophil cationic protein levels in paediatric atopic asthma
Clinical Drug Investigation, 2006, 26 (6), 351–356
7. Kopřiva F., Szotkowská J., Ordeltová M., Zápalka M.. Percentage of eosinophils with surface CD44 and levels of eosinophil cationic protein in the peripheral blood in children with bronchial asthma and their changes after montelukast therapy Allergy Asthma Proc, 2006, 27, 4, 378–382(5)
8. Kopřiva F., Michálková M., Zápalka M., J. Malý J. Potato crisps without pancreatic extracts supplements: a potential cause of the distal intestinal obstruction in cystic fibrosis. Eur J Pediatr. 2007, 166, 969 – 970
9. Kopřiva F., Szotkowská J., Zápalka M., Látalová M., Slezáková L., Smatanová D. A comparison of results of histamine and methacholine bronchoprovocation testing using the dosimetric method with MedicAid and DeVilbiss nebulizers measured with oscillometry in asthmatic children.
J Asthma 2007, 44, 267 – 271
10. Gruber C., Warner J., Hill D., Bauchau V; EPAAC Study Group. Early atopic disease and early childhood immunization – is there a link? Allergy 2008, 63, 1464 – 72
11. de Benedictis FM, Franceschini F, Hill D, Naspitz C, Simons FE, Wahn U, Warner JO, de Longueville M; EPAAC Study Group. The allergic sensititization in infants with atopic eczema from different countries. Allergy. 2009 Feb;64(2­):295–303.
12. Kopřiva F., Džubák P. Potěšil J., Hajdůch M. The anti-inflammatory effects of inhaled corticosteroids versus antileukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children. J Asthma 2009